I relate to this coming from a big family to begin with. But I embraced the in-laws and was the communicator and coordinator for 20 years. Many enjoyed my hosting. But once I got divorced, it all disappeared. I stay in touch with one of his cousin's every once in a while. It's sad, but that's the price I paid for walking away from my marriage.
In your case, if you feel any personal connection with any one of those inlaws left, there is no harm in including them in events. Often, we women are the thread that hold the family together. Most men don't initiate or coordinate family gatherings. Do what feels right to you.